Wavefront Shaping for Biomedical Imaging   

This highly recommended comprehensive survey of disparate techniques to directly or indirectly sense and modify wavefronts, and thereby decrease the effects of aberrations and light scatter on the contrast and the imaging depth for biological imaging.

The prescient work of Josef Bille and his collaborators in the late 1980s led to the specular advances in human retinal imaging. Today's major innovations are on in vivo, deep-tissue imaging of developing organisms and highly scattering specimens such as the brain.

The contributors to this book describe the theory, instrumentation and algorithms, and the limitations for specific specimens. The text description of the instrumentation is clear and is augmented with figures of the design components and references that provide deeper insights. In addition to wavefront shaping, there are alternatives such as the three-photon microscopy of in vivo brains, as developed in Chris Xu's laboratory.

Perusal of this exciting book suggests that combinations of wavefront-shaping techniques with vortex light beams may result in significant advances of deep-tissue imaging of highly scattering live specimens.  

Review by Barry R. Masters, Fellow of AAAS, OSA and SPIE

The opinions expressed in the book review section are those of the reviewer and do not necessarily reflect those of OPN or OSA.


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