Multiscale Photoacoustic Tomography

Lei Li, Li Lin and Lihong V. Wang

Photoacoustic tomography can bridge microscopic insights and macroscopic observations, providing imaging over a range of spatial scales—from organelles and cells to tissues, small animals and human organs.

figureHigh-resolution molecular imaging of a mouse whole body using single-impulse panoramic photoacoustic computed tomography. [Lei Li et al., Nat. Biomed. Eng. 1, 0071 (2017)]

Biomedical imaging has revolutionized modern medical care and life science. Peering inside complex biological systems, imaging technologies have recently achieved finer spatiotemporal resolution, richer contrast, deeper penetration, and greater detection sensitivity and specificity. The result has been an ever-more-comprehensive view of biological structures and functions.

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