April 2018 Issue
Feature Articles
Optogenetics: Controlling Neurons with Photons
An advancing field of neuroscience uses light to understand how the brain works and to create new tools to treat disease.
by Valerie C. CoffeyMultiscale Photoacoustic Tomography
Photoacoustic tomography can bridge microscopic insights and macroscopic observations, providing imaging over a range of spatial scales—from organelles and cells to tissues, small animals and human organs.
by Lei Li, Li Lin and Lihong V. WangOptical Tweezers Bring Micromachines to Biology
Optical tweezers, using focused laser beams to manipulate objects on the nano- and microscale, allow exploration of a world of curiosities at the borderline between physics and biology.
by I.A. Favre-Bulle, S. Zhang, A.V. Kashchuk, I.C.D. Lenton, L.J. Gibson, A.B. Stilgoe, T.A. Nieminen and H. Rubinsztein-DunlopDepartments and Columns
This month’s cover story looks at optogenetics, a field of neuroscience helping to advance our understanding of the differences between the healthy and diseased brain. As the world population ages, knowledge of neurodegenerative diseases is becoming increasingly important. Countries around the world are investing large sums of money to develop new technologies toward a lifelong healthy brain—but much more is needed.
Building a Photonics Cluster—From Scratch
The ambitious Mexican Photonics Initiative finds a home for its proposed industry hub.
Taking Control of Your Job Search
Alan E. Willner advocates for an “ABC” approach to job hunting that maximizes opportunity and minimizes regret.
Also in this Issue
Urbasi Sinha wins ICO/ICTP award; Optical Society of Korea meeting; thank you, editors; Bennett joins the Florida Institute of Technology; OSA Fellow member stories; encouraging young scientists; IONS 2018 locations announced; March for Science 2018; thank you, volunteers.

![Manual probe system with needles for test of semiconductor on silicon wafer. [A. Morozov / Getty]](https://opnmedia.blob.core.windows.net/$web/opn/media/images/articles/2025/1125/departments/202511-cover-web.jpg?ext=.jpg)
![Researcher Clara Saraceno in the lab. [Image by Carsten Behler Photography]](https://opnmedia.blob.core.windows.net/$web/opn/media/images/articles/2025/1025/departments/202510-cover-web.jpg?ext=.jpg)