Interferometric Synthetic Aperture Microscopy: Microscopic Laser Radar

Tyler S. Ralston, Gregory L. Charvat, Steven G. Adie, Brynmor J. Davis, P. Scott Carney and Stephen A. Boppart

Using instruments from optical coherence tomography and the principles of synthetic aperture radar, researchers have developed a new method for reconstructing 3-D optical images. Doctors may soon be able to use this approach as a noninvasive diagnostic tool in clinical settings.


figureMicroscopic 3-D optical imaging provides guidance to tomorrow’s doctors during surgical interventions.

In many clinical scenarios, doctors require high-resolution visualization of tissues and their underlying cellular structures. Perhaps the most common example is for the identification, diagnosis and treatment of cancer. In such cases, clinicians typically take tissue biopsies, which are then processed in a pathology lab and examined under a microscope.

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