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Stimulated Raman Scattering Improves Video of Living Tissue

Patricia Daukantas

Researchers have sped up the stimulated Raman spectroscopy imaging process to make real-time imaging of surface tissue cells practical.

Scatterings imageLabel-free tissue imaging of a sebaceous gland wrapping around a hair in the viable epidermis of mouse skin. Image in red shows lipid-rich gland cells; green image shows new protein-rich structures such as a hair in the center; blue shows inverse image contrast from the gland.

Still images work for some biomedical applications, but video provides scientists with real-time imaging of drug diffusion in tissues, among other uses. Researchers have now speeded the stimulated Raman spectroscopy (SRS) imaging process to make real-time imaging of surface tissue cells practical (Science 330, 1368).

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Publish Date: 01 March 2011


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