Calibrating Beam Trajectories for Opthalmic Imaging

In OPN’s December “Optics in 2022” review of interesting research, researchers from Nicolaus Copernicus University in Toruń, Poland, highlighted recent work that laid out a method to achieve resolution beyond the diffraction limit in scanning laser ophthalmoscope (SLO) measurements. The method involves calibration of the instrument through an efficient, computationally aided protocol that measures the scanning beam at every point in its trajectory, and that eliminates uncorrelated noise and distortions. The team believes the work could open new avenues in clinical ophthalmology, including in the detection of biomarkers for early signs of neurodegenerative disease. This video shows an image reconstruction using calibrated scanning trajectories.